Real Barrier Cica Relief Rx Fade In Serum 50ml pump bottle, a fragrance-free K-beauty cica serum with a full centella triterpene complex, 5 percent niacinamide, sea buckthorn, and licorice
Good choice for Sensitivity
What Makes This Different

It is the rare Real Barrier product that is genuinely fragrance-free and essential-oil-free, pairing a complete centella triterpene complex with 5 percent niacinamide, sea buckthorn, and licorice. That makes it the brand's most sensitive-skin-appropriate serum and a true calming-and-fading treatment rather than a scented soother.

Real Barrier

Real Barrier Cica Relief Rx Fade In Serum Review

Fragrance-Free Cica Recovery Serum
serum serum k beauty Paraben Free Fungal Acne Safe Cruelty Free Vegan

The standout of Real Barrier's lineup and a genuinely excellent cica serum: a full centella triterpene complex plus 5 percent niacinamide, sea buckthorn, and licorice in a fragrance-free, essential-oil-free base. It calms redness fast and fades lingering marks over weeks, and crucially it drops the essential oils that compromise so many of the brand's other products. For sensitive, reactive skin, this is the one to reach for.

$30.40
1.69 fl oz / 50ml
4.6 ★★★★★
1,100 reviews
Made in South Korea Launched 2022 All-year use PAO: 12 months
Buy at Amazon ♥
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Verdicts

How well it fits each concern

Verdict by concern tap a concern for the case

Good choicefor SensitivityNo fragrance, drying alcohol, declarable allergens or sensitising preservatives in this serum — the profile sensitive skin looks for.Not yet assessedGentleNo reviews collected yet

The case for it

  1. Full Centella Complex has been researched for this concern and the evidence does not support it.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries none of the triggers this concern is sensitive to.

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Good choice” is the verdict on 1,938 of 45,024 concern verdicts across the catalog; rule F2 decided 1,938 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
F2 — Gentle = no weighted deduction fired and fit ≥ 90. · the full register
Carrying active
Full Centella Complex
Standing
none
Form
plausible — studied range 0.05%, from the trials on the row; needs leave-on contact
Tolerability
gentle

The studies behind the evidence row

All sensitivity products →
Good choicefor Compromised Skin BarrierNiacinamide is a reference standard by mechanism for compromised skin barrier; this serum carries it at 5%.Moderate evidenceGentleNo reviews collected yet

The case for it

  1. Niacinamide has trial-supported standing for this concern.
  2. It is present at an effective concentration, declared or high in the ingredient list.
  3. The formula carries none of the triggers this concern is sensitive to.

Same rule for everyone. “Good choice” is the verdict on 9,564 of 45,024 concern verdicts across the catalog; rule R5 decided 9,072 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
R5 — Trial-supported or guideline-supported active, adequately or plausibly dosed. · the full register
Carrying active
Niacinamide
Standing
supported — its mechanism is established
Form
adequate (declared 5%) — studied range 2%, from the trials on the row; needs leave-on contact; judge it after ~8 weeks
Tolerability
gentle
Row checked
against its sources on July 17, 2026 (evidence table ev-2026.09-r228)

The studies behind the evidence row

All compromised skin barrier products →
Unprovenfor Post-ProcedureAllantoin has early or mechanistic evidence for post procedure — a reasonable bet, not a recommendation; the other actives here are not yet assessed for it.Limited evidenceGentleNo reviews collected yet

The case for it

  1. Allantoin has early or mechanistic evidence for this concern, not trial-backed standing.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries none of the triggers this concern is sensitive to.

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Unproven” is the verdict on 1,111 of 45,024 concern verdicts across the catalog; rule R9 decided 1,111 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
R9 — Plausible-tier actives alone do not earn a recommendation, and 'not for this' would overstate the case against them. 'Unproven' with the evidence dots lets the reader judge the bet (added 0.2.0 after the first shadow run put a 10% niacinamide serum at 'not for this' for hyperpigmentation). 0.5.0: the closing clause reads the other heroes — "nothing else here addresses it" only when every other active has a researched 'none' row; "not yet assessed" when that is the truth. Rows whose dots read moderate or better now reach R9p first. · the full register
Carrying active
Allantoin
Standing
plausible — trials support it
Form
plausible — studied range 0.5–2%, from the OTC monograph or label; needs leave-on contact
Tolerability
gentle
Row checked
against its sources on July 17, 2026 (evidence table ev-2026.09-r228)

The studies behind the evidence row

All post-procedure products →
Good choicefor HyperpigmentationNiacinamide is a trial-supported active for hyperpigmentation; this serum carries it at 5%.Moderate evidenceGentleNo reviews collected yet

The case for it

  1. Niacinamide has trial-supported standing for this concern.
  2. It is present at an effective concentration, declared or high in the ingredient list.
  3. The formula carries none of the triggers this concern is sensitive to.

Same rule for everyone. “Good choice” is the verdict on 9,564 of 45,024 concern verdicts across the catalog; rule R5 decided 9,072 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
R5 — Trial-supported or guideline-supported active, adequately or plausibly dosed. · the full register
Carrying active
Niacinamide
Standing
supported — trials support it
Form
adequate (declared 5%) — studied range 2–5%, from the trials on the row; needs leave-on contact; judge it after ~8 weeks
Tolerability
gentle
Row checked
against its sources on July 17, 2026 (evidence table ev-2026.09-r228)

The studies behind the evidence row

All hyperpigmentation products →
Unprovenfor RosaceaNiacinamide has early or mechanistic evidence for rosacea — a reasonable bet, not a recommendation; the other actives here are not yet assessed for it.Limited evidenceGentleNo reviews collected yet

The case for it

  1. Niacinamide has early or mechanistic evidence for this concern, not trial-backed standing.
  2. It is present at an effective concentration, declared or high in the ingredient list.
  3. The formula carries none of the triggers this concern is sensitive to.

What would change this: Trial evidence for the active on this concern would move this from a bet to a recommendation.

Same rule for everyone. “Unproven” is the verdict on 1,111 of 45,024 concern verdicts across the catalog; rule R9 decided 1,111 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
R9 — Plausible-tier actives alone do not earn a recommendation, and 'not for this' would overstate the case against them. 'Unproven' with the evidence dots lets the reader judge the bet (added 0.2.0 after the first shadow run put a 10% niacinamide serum at 'not for this' for hyperpigmentation). 0.5.0: the closing clause reads the other heroes — "nothing else here addresses it" only when every other active has a researched 'none' row; "not yet assessed" when that is the truth. Rows whose dots read moderate or better now reach R9p first. · the full register
Carrying active
Niacinamide
Standing
plausible — trials support it
Form
adequate (declared 5%) — studied range 2%, from the OTC monograph or label; needs leave-on contact; judge it after ~8 weeks
Tolerability
gentle
Row checked
against its sources on July 17, 2026 (evidence table ev-2026.09-r228)

The studies behind the evidence row

All rosacea products →

Also listed for Dullness — the actives here (Niacinamide, Allantoin, Adenosine, Centella Asiatica) are in our research queue for that concern; there is no verdict until their evidence rows are written. That is a gap in our table, not a mark against the product.

A verdict is DermApproved’s assessment of how well a product’s ingredients fit a concern — never a claim about what the product treats. Evidence dots and collected reviews sit beside it and are never blended in. Rules 0.5.1 · evidence table ev-2026.09-r228 · how we decide

Assessment

Pros & Cons

Pros

  • ✓ Genuinely fragrance-free and essential-oil-free
  • ✓ Full centella triterpene (TECA) complex, not a token extract
  • ✓ 5 percent niacinamide to fade redness and marks
  • ✓ Calms active redness and irritation quickly
  • ✓ Excellent gentle buffer for retinoids and acids
  • ✓ Suitable for virtually all skin, including sensitive
  • ✓ Generous 50ml size and clean, focused formula

Cons

  • ✗ Mark-fading is gradual, not dramatic
  • ✗ Deliberately plain for those wanting more actives
  • ✗ Mid-range price for 50ml
  • ✗ Soothing-and-fading focus rather than a multi-tasker
  • ✗ May need a stronger partner for significant pigmentation
Review

Full Review

After working through much of the Real Barrier catalog, a frustrating pattern emerges: time and again, a thoughtfully formulated product aimed at sensitive, barrier-compromised skin is quietly sabotaged by a blend of essential oils, bergamot here, lavender there, a whole bouquet in the Intense Moisture Toner. So it is genuinely refreshing to arrive at the Cica Relief Rx Fade In Serum and find that the brand finally left the fragrance out. This serum is fully fragrance-free and essential-oil-free, and that single decision transforms it from a nice idea into the product the rest of the line keeps promising to be. For irritated, reactive skin, this is the one that actually delivers.

What makes it more than just an unscented soother is the quality of its cica. The word cica gets slapped on everything these days, often backed by nothing more than a token drop of centella extract. This serum does it properly: it includes the whole centella asiatica extract plus all four of its key purified triterpenes, asiaticoside, asiatic acid, madecassic acid, and madecassoside, the complex often labeled TECA. That full fraction is the form with the strongest evidence for soothing, calming inflammation, and supporting skin recovery, and it is dosed prominently here. If you have used watery 'cica' products that did nothing, the difference with a complete complex like this is noticeable: redness genuinely looks calmer, and reactive skin feels more settled.

The 'fade in' part of the name comes from the second pillar: niacinamide, placed fourth on the list at around 5 percent. This is where the serum goes beyond calming into actual correction. Niacinamide is one of the best-evidenced actives for evening tone and, paired with the centella, it works on the specific problem this serum targets, the lingering redness and brown post-blemish marks left behind after irritation or breakouts settle. The centella calms the active inflammation; the niacinamide helps fade what it leaves behind. It is a smart, complementary pairing, rounded out with antioxidant sea buckthorn, soothing licorice and allantoin, adenosine, and a touch of the brand's pseudo-ceramide for barrier support. The ingredient list is refreshingly short and entirely on-message, every component serving the soothe-and-fade goal with nothing extraneous.

Using it is exactly what sensitive skin wants: uneventful in the best way. The texture is a lightweight, slightly gel-like serum that absorbs cleanly with no scent and no sting, and most people feel an immediate sense of relief on irritated skin. There is no purge, no adjustment, no risk. Active redness looks reduced quickly, while the fading of marks and the evening of tone build gradually over four to eight weeks of consistent use. Because it is so gentle and fragrance-free, it also doubles as one of the better buffer serums you can own, layer it with a retinoid or an exfoliating acid to calm the skin and support the barrier while you build tolerance, and it plays that supporting role beautifully.

If there is a limitation, it is simply that this is a focused, gentle treatment rather than a dramatic one. The mark-fading is real but gradual, as all gentle brightening is, and someone with significant pigmentation may want a more aggressive approach alongside it. The formula is also deliberately plain, which is the entire point for reactive skin but may feel sparse to someone who wants a long, flashy ingredient list. And at around thirty dollars for 50 milliliters, it is mid-range rather than cheap, though the generous size and the genuine quality of the cica complex justify it. These are quibbles, not real faults.

Value, in context, is good. The 50 milliliter size is generous for a treatment serum, larger than the 30 milliliter ampoules common in the range, so it lasts, and you are getting a complete centella complex plus functional niacinamide in a clean, fragrance-free base, which is genuinely hard to find at any price. Dedicated cica serums of this quality often cost more, and the fragrance-free formulation adds real value for the sensitive skin that needs it. Real Barrier, as an established barrier-repair brand, prices it sensibly for what it is.

The recommendation is the easiest in the batch. For sensitive, reactive, rosacea-prone, or post-procedure skin, and for anyone dealing with redness and post-blemish marks who wants a gentle, fragrance-free way to calm and fade them, this is an excellent, easy choice, and the best product Real Barrier makes for that purpose. It is the rare case where the brand's barrier-repair philosophy and its formulation fully align, with no essential-oil asterisk to qualify the praise. If you have been let down by scented 'soothing' products before, this is the one that finally gets it right. It is also a reassuring example of what this brand can do when it trusts its actives to carry a product without a scent. Stripped of the essential oils that complicate so much of its catalog, the formula reads as confident and purposeful, every ingredient pulling toward the same soothe-and-fade goal, and one hopes it points the direction the rest of the range eventually follows.

Formula

Key Ingredients

The hero actives that drive this product's performance.

IngredientFunctionEvidence
Full Centella Complex (TECA: Asiaticoside, Asiatic Acid, Madecassic Acid, Madecassoside) Rather than a crude extract, this serum supplies the full purified centella fraction, all four key triterpenes plus the whole-plant extract, the most complete soothing-and-repair form of cica, which is what makes this genuinely effective at calming redness and supporting recovery in irritated skin. Limited for Post-Procedure
Niacinamide (5%) (5%) Placed fourth on the list at around 5 percent, it is the 'fade in' engine, working with the centella to even tone and gradually fade the lingering redness and post-blemish marks that the centella calms, while reinforcing the barrier. Established mechanism for Compromised Skin Barrier · established mechanism
Sea Buckthorn (Hippophae Rhamnoides) Extract An antioxidant, carotenoid-rich fruit extract that supports the formula's recovery and antioxidant side, complementing the centella in soothing and conditioning stressed skin. Not yet assessed
Allantoin A classic skin-conditioning soother that reinforces the calming, barrier-comforting intent, helping keep the serum gentle on reactive and compromised skin. Limited for Post-Procedure
Adenosine A well-tolerated cell-signaling ingredient that adds a subtle smoothing, recovery-supporting benefit without any irritation, fitting the serum's gentle, repair-focused character. Not yet assessed
Licorice Root (Dipotassium Glycyrrhizate) A soothing, anti-inflammatory licorice derivative that adds a gentle brightening note alongside the niacinamide, helping calm and even the look of irritation-prone skin. Limited for Hyperpigmentation
Full INCI List

Water/Aqua, Propanediol, Butylene Glycol, Niacinamide, Glycerin, Triethyl Citrate, 1,2-Hexanediol, Centella Asiatica Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Madecassoside, Hippophae Rhamnoides Fruit Extract, Allantoin, Xanthan Gum, Lecithin, Ammonium Acryloyldimethyltaurate/VP Copolymer, Dipotassium Glycyrrhizate, Myristoyl/Palmitoyl Oxostearamide/Arachamide MEA, Adenosine, Arginine, Sodium Citrate, Hydroxyacetophenone

Safety & Formulation Facts
✓ Pregnancy Safe ✓ Fragrance Free✓ Alcohol Free✓ Oil Free✓ Silicone Free✓ Paraben Free✓ Sulfate Free✓ Cruelty Free✓ Vegan✓ Fungal Acne Safe
Compatibility

Skin Match

Best For
Works For
Routine Step

serum

Time of Day

AM & PM

Layering Tips

Smooth a few drops on after cleansing and toner, before moisturizer, morning and night. Because it is fragrance-free and purely soothing, it layers well with almost anything and makes an excellent buffer alongside stronger actives, apply it before or after a retinoid or exfoliant to calm and support the barrier.

Results Timeline

Immediate: visibly calmer, more comfortable skin and reduced-looking redness. Over 4-8 weeks, the niacinamide and centella work together to fade lingering redness and post-blemish marks and even overall tone.

Pairs Well With
moisturizersunscreenserumretinoid
Planning a combo? Check it against what you already use
Sample AM Routine
  1. Gentle cleanser
  2. Hydrating toner
  3. Real Barrier Cica Relief Rx Fade In Serum
  4. Moisturizer
  5. Sunscreen
Sample PM Routine
  1. Cleanser
  2. Hydrating toner
  3. Real Barrier Cica Relief Rx Fade In Serum
  4. Moisturizer
Evidence

Science & Expert Perspective

The Science

This serum pairs two of the better-evidenced soothing and tone actives in a notably clean formula. Centella asiatica is included not just as a crude extract but as the full set of its bioactive triterpenes, asiaticoside, asiatic acid, madecassic acid, and madecassoside (collectively TECA or 'cica' complex), which have the strongest evidence among centella forms for anti-inflammatory, wound-healing, antioxidant, and barrier-supporting effects; using the purified complex rather than a token extract is what makes the soothing claim credible. Niacinamide at approximately 5 percent is well within its evidence-backed range for reducing hyperpigmentation (by inhibiting melanosome transfer), improving barrier function, and evening tone, which directly supports the 'fade in' goal of reducing post-inflammatory redness and marks; the pairing of an anti-inflammatory cica complex with niacinamide is a rational approach to post-inflammatory erythema and hyperpigmentation, where calming the inflammation and fading the residual discoloration are complementary aims. Sea buckthorn adds antioxidant, carotenoid-rich support with more limited evidence, and licorice (dipotassium glycyrrhizate), allantoin, and adenosine contribute additional well-tolerated soothing and recovery benefits, with a pseudo-ceramide for barrier support. Critically, the formula is fragrance-free and essential-oil-free, removing the sensitization risk that compromises many soothing products, which is itself an evidence-aligned choice for reactive and barrier-impaired skin. The honest read is a focused, well-constructed serum whose two lead actives are genuinely supported for its intended use, in a base appropriate for the sensitive skin it targets.

Dermatologist Perspective

Centella asiatica and niacinamide are both frequently recommended in clinical practice, centella (especially its purified triterpenes) for soothing inflammation and supporting barrier recovery, and niacinamide for evening tone and reducing post-inflammatory hyperpigmentation. A serum that combines a full centella complex with around 5 percent niacinamide in a fragrance-free, essential-oil-free base aligns closely with the kind of gentle, supportive treatment dermatologists suggest for sensitive, rosacea-prone, post-procedure, and post-acne skin dealing with redness and marks. The absence of fragrance is a meaningful advantage and addresses the main caution that applies to many of the brand's other products. Clinicians would frame the mark- and redness-fading as gradual and best paired with diligent daily sunscreen, which is essential for any improvement in post-inflammatory pigmentation, and would note that significant pigmentation may warrant additional targeted treatment. As a low-risk soothing-and-fading step, including as a buffer alongside retinoids or acids, it fits standard sensitive-skin guidance well.

Guidance

Usage & Recommendations

How to Use

Apply a few drops after cleansing and toner, before moisturizer, morning and night, pressing it evenly over the face with extra attention to areas of redness or marks. Because it is fragrance-free and purely soothing, it layers well with almost anything and works as a buffer for stronger actives, apply it before or after a retinoid or exfoliant to calm the skin. Give it four to eight weeks for the redness- and mark-fading to show, and always follow with sunscreen in the morning, since sun protection is essential for any improvement in post-inflammatory pigmentation.

Value Assessment

At around thirty dollars for a generous 50 milliliters, this is fair to good value for a focused cica-and-niacinamide treatment, especially given the quality of the actives, a full centella triterpene complex and functional 5 percent niacinamide, in a genuinely fragrance-free base that is hard to find at any price. The 50 milliliter size is larger than the 30 milliliter ampoules common in the range, so it lasts well with twice-daily use. As an established barrier-repair brand from Neopharm rather than a hype label, Real Barrier prices it in line with the formula. For sensitive skin that struggles to find effective soothing-and-fading products without fragrance, the value is especially strong, since the clean formulation removes a risk that cheaper alternatives often carry.

Who Should Buy

This is an excellent choice for sensitive, reactive, rosacea-prone, or post-procedure skin, and for anyone dealing with lingering redness and post-blemish marks who wants a gentle, fragrance-free way to calm and fade them. It also suits anyone who wants a reliable soothing buffer to pair with retinoids or exfoliating acids.

Who Should Skip

It is genuinely suitable for almost everyone, but skip it if you want a dramatic, fast-acting pigmentation treatment, since the fading here is gentle and gradual and significant discoloration may need a stronger partner. Those who prefer a richer, multi-tasking serum with a long active list may also find this focused formula too pared-back for their taste.

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Details

Product Details

Texture

A lightweight, slightly gel-like serum that spreads smoothly and absorbs to a soft, calm, non-tacky finish

Scent

Fragrance-free and essential-oil-free, with only a faint neutral base smell

Packaging

A 50ml pump bottle dispensing a controlled dose of the clear serum

Finish
lightweightfast-absorbingnon-greasysatin
What to Expect on First Use

It applies light and calming, with no sting or scent, and most people feel an immediate sense of relief on irritated or reactive skin. There is no purge or adjustment period; redness looks reduced quickly, while the fading of marks and tone-evening builds gradually over weeks.

How Long It Lasts

Around 2-3 months applied morning and night from the generous 50ml bottle

Period After Opening

12 months

Opened yours? Track the toss-by date
Best Season

All Year

Certifications
cruelty-free
Background

The Story Behind This Product

The Cica Relief Rx range is Real Barrier's recovery line for irritated, reactive skin, and this 'Fade In' serum extends cica beyond simple calming to address the redness and marks left behind. Tellingly, the brand stripped out the fragrance and essential oils that appear across much of its catalog, recognizing that genuinely compromised skin needs them gone.

About Real Barrier Established Brand (5–20 years)

Real Barrier, the barrier-repair line from Neopharm (maker of ATOPALM), built its Cica Relief Rx range for irritated, reactive skin. Notably, and unlike much of the brand's catalog, this serum is fully fragrance-free and essential-oil-free, making it the most sensitive-skin-appropriate product in the line. It is stocked on Amazon and at K-beauty retailers.

Brand founded: 2015 · Product launched: 2022
Myth vs. Reality

Common Myths

Myth

All cica products are interchangeable soothing creams.

Reality

Cica quality varies enormously. A crude centella extract is far weaker than the full triterpene complex, asiaticoside, asiatic acid, madecassic acid, and madecassoside, used here. Combined with 5 percent niacinamide in a fragrance-free base, this is a genuine recovery treatment, not just a generic 'cica' label.

FAQ

Frequently Asked Questions

What does the Real Barrier Cica Relief Rx Fade In Serum do?

It calms irritated, reactive skin and gradually fades lingering redness and post-blemish marks. A full centella triterpene complex soothes and supports recovery, while 5 percent niacinamide evens tone and reinforces the barrier, all in a fragrance-free, essential-oil-free formula.

Is this Real Barrier serum actually fragrance-free?

Yes. Unlike many products in the Real Barrier range, this serum is genuinely fragrance-free and essential-oil-free, which makes it the brand's most suitable serum for sensitive, reactive, rosacea-prone, and post-procedure skin.

What is the difference between the centella extract and the 'TECA' complex here?

This serum includes both the whole centella extract and its four purified active triterpenes, asiaticoside, asiatic acid, madecassic acid, and madecassoside, often called TECA or cica complex. That full fraction is more potent and consistent for soothing and skin recovery than a basic centella extract alone.

Can I use this serum with retinol or exfoliating acids?

Yes, and it is an excellent pairing. Because it is purely soothing and fragrance-free, it makes a great buffer for stronger actives, layered before or after a retinoid or exfoliant to calm the skin and support the barrier while you build tolerance.

How long until it fades redness and post-acne marks?

Calming of active redness is often immediate, but fading lingering post-blemish redness and marks is gradual, typically four to eight weeks of consistent use as the niacinamide and centella work together. Daily sunscreen is essential to let that fading show.

Reviews

What Reviewers Tend to Say

Recurring themes our editors read across retailer reviews of this product — summaries in our words, not quotations, and not a substitute for your own patch test.

Common Praise

Genuinely calms redness and irritation

Fragrance-free and very gentle

Fades post-blemish marks over time

Lightweight, comfortable texture

Great buffer for stronger actives

Common Complaints

Results on marks are gradual

Plain formula for those wanting more

50ml at a mid-range price

Soothing rather than dramatic

Notable Endorsements
Popular fragrance-free cica recovery serumStocked on Amazon and major K-beauty retailers
Appears In
Best Serums for HyperpigmentationBest Serums for Dark SpotsBest Centella Serums
Related Conditions
sensitivitycompromised skin barrierpost procedurehyperpigmentationrosacea
Related Ingredients
centella asiaticaniacinamidesea buckthornallantoinlicorice root