Klairs Vitamin PDRN Bouncy Pore Serum 35 mL bottle with dropper
Promising for Large Pores
What Makes This Different

Most pore serums lean on niacinamide alone. This one stacks the moment's two buzziest actives — PDRN (here in a vegan, plant-derived Sodium DNA form) and a five-type vitamin C complex — onto a base of three peptides, niacinamide and astaxanthin. It targets pores through firmness and elasticity, not just oil control.

Klairs

Klairs Vitamin PDRN Bouncy Pore Serum Review

PDRN Trend Pick
serum serum k beauty Paraben Free Cruelty Free Vegan

A heavily loaded pore serum that rides the PDRN wave intelligently — pairing a vegan, plant-derived PDRN and a five-form vitamin C complex with three peptides, niacinamide and astaxanthin, all fragrance-free. The well-established actives carry it; PDRN and NMN are promising trend ingredients whose topical evidence is still being written.

$31.00
35 mL / 1.18 fl oz
4.3 ★★★★★
280 reviews
Made in South Korea Launched 2025 All-year use PAO: 12 months
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Run it through our tools Clashes with my routine? Pregnancy-safe? Find a cheaper dupe Patch-test it first

A recent Klairs launch on the PDRN trend, this serum has little independent feedback yet. The grade leans on the formula and Klairs's long history more than on user data.

Verdicts

How well it fits each concern

Verdict by concern tap a concern for the case

Promisingfor Large PoresNiacinamide has trial-level evidence for large pores but no guideline or regulatory standing yet — promising, short of a recommendation; the other actives here are not yet assessed for it.Moderate evidenceGentleNo reviews collected yet

The case for it

  1. Niacinamide has trial-level evidence for this concern but no guideline or regulatory standing yet.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries none of the triggers this concern is sensitive to.

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Promising” is the verdict on 7,858 of 45,024 concern verdicts across the catalog; rule R9p decided 7,858 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
R9p — 0.5.0: 'Unproven' beside three filled dots read as one question answered twice with opposite words (7,018 rows). The chip measures standing, the dots measure trial volume; where the row carries at least one RCT or a tier-2 source (moderate dots) and the active is present at a working level, the honest word is Promising. Unproven is reserved for plausible-standing rows with limited or weak evidence, or an under-dosed form. Same rank as Unproven — a bet either way; the dots order them. · the full register
Carrying active
Niacinamide
Standing
plausible — trials support it
Form
plausible — studied range 4%, from the trials on the row; needs leave-on contact; judge it after ~8 weeks
Tolerability
gentle
Row checked
against its sources on July 17, 2026 (evidence table ev-2026.09-r228)

The studies behind the evidence row

All large pores products →
Promisingfor AgingNiacinamide has trial-level evidence for aging but no guideline or regulatory standing yet — promising, short of a recommendation; the other actives here are not yet assessed for it.Moderate evidenceGentleNo reviews collected yet

The case for it

  1. Niacinamide has trial-level evidence for this concern but no guideline or regulatory standing yet.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries none of the triggers this concern is sensitive to.

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Promising” is the verdict on 7,858 of 45,024 concern verdicts across the catalog; rule R9p decided 7,858 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
R9p — 0.5.0: 'Unproven' beside three filled dots read as one question answered twice with opposite words (7,018 rows). The chip measures standing, the dots measure trial volume; where the row carries at least one RCT or a tier-2 source (moderate dots) and the active is present at a working level, the honest word is Promising. Unproven is reserved for plausible-standing rows with limited or weak evidence, or an under-dosed form. Same rank as Unproven — a bet either way; the dots order them. · the full register
Carrying active
Niacinamide
Standing
plausible — trials support it
Form
plausible — studied range 4–5%, from the trials on the row; needs leave-on contact; judge it after ~8 weeks
Tolerability
gentle
Row checked
against its sources on July 17, 2026 (evidence table ev-2026.09-r228)

The studies behind the evidence row

All aging products →
Supporting rolefor DehydrationNothing here targets dehydration directly; humectant hydration is the recognised companion to treating it, and this serum does that without known triggers.Not yet assessedGentleNo reviews collected yet

The case for it

  1. Niacinamide has no evidence row yet for this concern — it is in the research queue.
  2. The formula carries none of the triggers this concern is sensitive to.

What would change this: A researched evidence row for the lead active would replace this with a verdict.

Same rule for everyone. “Supporting role” is the verdict on 8,197 of 45,024 concern verdicts across the catalog; rule R8 decided 4,250 of them. Unchanged since September 5, 2026, engine 5.1.1.

Brand or formulator? Disclose a concentration or correct a fact →

Show the work
Rule
R8 — The category's job (barrier care, humectant hydration, gentle cleansing, photoprotection) is the documented supportive role for this concern. This is the honest verdict for a moisturizer on an acne page. · the full register
Carrying active
Niacinamide
Standing
not assessed
Form
plausible
Tolerability
gentle
All dehydration products →

Also listed for Dullness and Rough Texture — the actives here (Niacinamide, Astaxanthin, Argireline (Acetyl Hexapeptide-8) are in our research queue for those concerns; there is no verdict until their evidence rows are written. That is a gap in our table, not a mark against the product.

Where our review and the verdict differ. The review below was written on the formulation and the published trials; the verdicts above apply the stricter standing test in our methodology — an active earns a recommendation only with guideline or regulatory standing for the concern. Where the two disagree, the verdict is DermApproved’s position.

A verdict is DermApproved’s assessment of how well a product’s ingredients fit a concern — never a claim about what the product treats. Evidence dots and collected reviews sit beside it and are never blended in. Rules 0.5.1 · evidence table ev-2026.09-r228 · how we decide

Assessment

Pros & Cons

Pros

  • ✓ Five-form vitamin C complex brightens and supports collagen
  • ✓ Niacinamide high in the formula genuinely refines the look of pores
  • ✓ Three peptides, including copper tripeptide-1, support elasticity
  • ✓ Vegan, plant-derived PDRN rather than the salmon-sourced original
  • ✓ Lightweight, fast-absorbing texture that layers cleanly
  • ✓ Fragrance-free, true to Klairs's sensitive-skin focus

Cons

  • ✗ PDRN and NMN are trend ingredients with limited topical evidence
  • ✗ Pure ascorbic acid can feel slightly sharp on reactive skin
  • ✗ 35 mL bottle is modest for twice-daily use
  • ✗ Pore results are gradual and cosmetic, never permanent
  • ✗ Not fungal-acne safe due to certain emulsifiers
Review

Full Review

PDRN had a viral 2025. It turned up on the label of seemingly every new K-beauty release, borrowed its credibility from clinics where polynucleotide injectables are a genuine treatment, and quickly became the ingredient brands reached for to make a launch feel current. So the fair question to bring to a PDRN serum is not whether the ingredient is fashionable — it plainly is — but what a trend ingredient is actually doing inside a leave-on bottle, and whether the rest of the formula stands up once you set the buzz aside. Klairs's Bouncy Pore Serum mostly answers that well, with one honest qualifier.

Begin with the PDRN itself, because Klairs took a notable angle on it. Rather than the salmon-derived polynucleotides of the original injectable concept, this serum uses a vegan, plant-derived form, listed on the label as Sodium DNA. PDRN-type polynucleotides are studied for supporting skin repair and elasticity, and here they anchor the 'bouncy' part of the name — the underlying idea being that slack, less firm skin makes pores look larger, so addressing firmness is itself a pore strategy. The qualifier worth stating: topical PDRN is a different proposition from injected PDRN, which reaches deeper skin layers directly. Its ability to penetrate and act from a serum remains an emerging research area. It is a promising trend ingredient, not a proven topical treatment, and the same caution applies to NMN, the niacinamide-related molecule also in the formula.

What carries the serum is the better-established supporting cast. A five-form vitamin C complex — pure ascorbic acid plus four gentler derivatives — gives the 'Vitamin' billing real substance, brightening dull, congested skin and supporting collagen, with the spread across stable derivatives meaning that potent L-ascorbic acid is not the sole, fragile source. Niacinamide sits high and does the core pore work: refining how pores look, helping regulate oil, reinforcing the barrier — the single most evidence-backed pore ingredient in the bottle. Three peptides, including the well-researched copper tripeptide-1, signal collagen and elasticity support, reinforcing the PDRN's firming angle, and astaxanthin closes the formula as a potent carotenoid antioxidant defending against the free-radical and UV stress that degrades collagen over time. Frame it plainly and the picture is clear: the well-established actives — vitamin C, niacinamide, peptides — are doing the dependable work, while PDRN and NMN are the promising, of-the-moment additions sitting on top.

Day to day, it behaves nicely. The texture is a lightweight, slightly gel-like serum that spreads easily, absorbs fast to a smooth, non-tacky finish, and leaves skin feeling cushioned and plump rather than coated. Reactive skin may register a brief, mild sharpness from the pure ascorbic acid in the complex, though nothing lingers. Klairs has formulated without added fragrance, in keeping with the brand's long-standing sensitive-skin focus, and the dropper makes it simple to take just a measured few drops. The limitations are about scale and pace: the 35 mL bottle is modest for twice-daily use, and the pore-and-elasticity benefits build quietly over six to eight weeks rather than appearing dramatically. Anyone expecting visible pore-shrinking will be let down — pore size is largely genetic, and what a serum like this does is make pores look smaller by clearing congestion, supporting elasticity and smoothing texture, a cosmetic and gradual change.

Fairness to the trend ingredients is due here as well. PDRN and NMN being unproven as topicals does not make them filler — they are not occupying space that a better-evidenced active should have. They are extra additions on a formula that was already complete without them, and if the emerging research on topical polynucleotides firms up, this serum will simply have been early.

A note on the 'pore' framing is also fair. The serum's angle — that pores look larger when skin loses firmness — is a legitimate, if partial, way to think about the concern, and it is the reason the formula leans on elasticity-support actives rather than oil-control alone. It will not out-perform a dedicated niacinamide-and-BHA approach on congestion-driven pores, but for skin where slackness is genuinely part of the picture, the firming logic is sound.

At a price around $31, it sits a notch above a basic niacinamide serum, and what the extra buys is the loaded, trend-aware formula — fair enough, provided you go in clear-eyed about which ingredients are carrying the load. Klairs has been formulating gentle, sensitive-skin K-beauty since 2010, with a long and well-reviewed track record, so this is a brand applying real experience to a fashionable brief rather than chasing a fad with no foundation underneath it. The review pool remains small — roughly 280 ratings averaging 4.3 stars — and early users single out the plumped, bouncy feel and the lightweight texture. Treated as a well-built brightening-and-pore serum, with the PDRN read as a promising bonus rather than the reason to buy, this is a reasonable, low-irritation choice — and a useful reminder that a loaded label is most trustworthy when the ingredients you can actually count on are sitting near the top of it.

Formula

Key Ingredients

The hero actives that drive this product's performance.

IngredientFunctionEvidence
PDRN The serum's trend-driving active, here in a vegan, plant-derived form listed on the label as Sodium DNA. PDRN-type polynucleotides are studied for supporting skin repair and elasticity; in this formula they anchor the 'bouncy' claim, working alongside the peptides to address the loss of firmness that makes pores look slack. Not yet assessed
5-Form Vitamin C Complex Five vitamin C types — pure ascorbic acid plus four gentler derivatives — give the serum its 'Vitamin' billing. The mix brightens dull, congested skin and supports collagen; spreading vitamin C across stable derivatives lets the serum include potent L-ascorbic acid without it being the sole, fragile source. Limited for Aging
Niacinamide Sits high on the list doing the core pore work — refining the look of pores, regulating oil and reinforcing the barrier. It is the most evidence-backed pore ingredient in the formula and pairs naturally with the vitamin C for tone. Limited for Large Pores
Peptide Complex (Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1) Three peptides, including the well-researched copper tripeptide-1, signal collagen and elasticity support — reinforcing the PDRN's firming work so that 'bouncy', tighter-looking skin reads around the pores rather than just smoother surface texture. Not yet assessed
NMN (Nicotinamide Mononucleotide) A niacinamide-related molecule and another trend ingredient, included for its energizing, antioxidant-supporting reputation. Its topical evidence is still emerging, so it functions here as a complementary addition to the better-established niacinamide rather than a proven active in its own right. Limited for Large Pores
Astaxanthin A potent carotenoid antioxidant that closes out the formula — it defends against the free-radical and UV stress that degrade collagen and enlarge the look of pores over time, supporting the serum's firming work from a protective angle. Not yet assessed
Full INCI List

Water (Aqua), Butylene Glycol, Glycerin, Niacinamide, 1,2-Hexanediol, Sodium DNA, Arginine, Carbomer, Polyacrylate Crosspolymer-6, Caesalpinia Spinosa Fruit Extract, Ethylhexylglycerin, Caprylyl Glycol, Adenosine, Kappaphycus Alvarezii Extract, Sodium Phytate, Polyglyceryl-10 Laurate, Glyceryl Acrylate/Acrylic Acid Copolymer, Polyglyceryl-4 Laurate, Nicotinamide Mononucleotide, PVM/MA Copolymer, Caprylyl/Capryl Glucoside, Prunella Vulgaris Extract, Opuntia Ficus-Indica Fruit Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Disodium EDTA, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hydrogenated Lecithin, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Sodium Ascorbyl Phosphate, Ascorbyl Glucoside, Ascorbyl Palmitate, Octyldodecanol, Astaxanthin

Safety & Formulation Facts
✓ Pregnancy Safe ✓ Fragrance Free✓ Alcohol Free✓ Oil Free✓ Silicone Free✓ Paraben Free✓ Sulfate Free✓ Cruelty Free✓ Vegan✗ Fungal Acne Safe
Potential Irritants
Vitamin C (ascorbic acid)
Compatibility

Skin Match

Best For
Works For
Routine Step

serum

Time of Day

AM & PM

Layering Tips

Apply after toner and before moisturizer, morning and evening. The serum already contains vitamin C, so there is no need to layer a separate vitamin C product over it. In the morning, always follow with sunscreen to protect the antioxidants and the brightening result.

Results Timeline

Early radiance and a smoother feel within 1-2 weeks. Improvement in the look of pores, elasticity and uneven tone builds gradually, typically over 6-8 weeks of consistent twice-daily use with daily sunscreen.

Pairs Well With
Hydrating tonerBarrier moisturizerNiacinamide essenceSunscreen SPF 30+
Planning a combo? Check it against what you already use
Sample AM Routine
  1. Gentle cleanser
  2. Hydrating toner
  3. Klairs Vitamin PDRN Bouncy Pore Serum
  4. Moisturizer
  5. Sunscreen SPF 30+
Sample PM Routine
  1. Oil cleanser
  2. Gentle cleanser
  3. Toner
  4. Klairs Vitamin PDRN Bouncy Pore Serum
  5. Moisturizer
Evidence

Science & Expert Perspective

The Science

This serum stacks actives with markedly different levels of evidence, and an honest read separates them. The well-established core is the strongest part. Vitamin C, in its pure L-ascorbic acid form and as several derivatives, is extensively studied for antioxidant activity, tyrosinase inhibition that supports brightening, and a role in collagen synthesis as a cofactor for the relevant enzymes; spreading it across five forms is a stability strategy, since L-ascorbic acid degrades readily while derivatives are more robust. Niacinamide has a deep evidence base for improving the appearance of enlarged pores, regulating sebum and strengthening the skin barrier — the most directly pore-relevant ingredient in the formula. Among the peptides, copper tripeptide-1 is the most researched, with data supporting skin-remodeling and collagen-related activity; acetyl hexapeptide-1 and -8 are signal-type peptides with promising but lighter evidence.

PDRN and NMN are the trend ingredients, and the evidence for them as topicals is genuinely thinner. PDRN — polydeoxyribonucleotide — has a real clinical footprint in injectable form, where polynucleotides are delivered into deeper skin and studied for tissue repair and elasticity. The serum's vegan, plant-derived version, labeled Sodium DNA, is a leave-on topical, and the open question is penetration: a large polynucleotide molecule's ability to cross the stratum corneum and act from a serum is an emerging, not settled, area of research. NMN (nicotinamide mononucleotide) is studied largely in the context of cellular metabolism and NAD+ biology; its topical skincare evidence is limited, so it functions here as a complementary addition rather than a proven active. Astaxanthin is a carotenoid with promising data as a potent antioxidant. The reasonable conclusion is that the dependable results come from the vitamin C, niacinamide and peptides, with PDRN and NMN as promising extras whose topical story is still being written. No product-specific clinical trials are available; this assessment rests on the evidence base for each ingredient class.

Dermatologist Perspective

PDRN has attracted considerable attention in dermatology and aesthetic medicine, but clinicians consistently draw a distinction between its injectable use — where there is genuine evidence for skin regeneration and healing — and its topical use, where the evidence is far thinner and penetration of the large molecules from a leave-on product is questioned. The general clinical view is that topical PDRN is promising but unproven, and that consumers should not equate a PDRN serum with a PDRN procedure. By contrast, the supporting actives in this serum are well regarded: niacinamide is a dermatology favorite for the appearance of pores and oil control, vitamin C is a long-established brightener and antioxidant, and peptides are considered low-risk, promising additions. On pore size, clinical consensus is firm — pores cannot be permanently shrunk topically, and products improve their appearance by managing oil, congestion and skin firmness. Dermatologists also tend to note that fragrance-free formulations suit sensitive skin, and that daily sunscreen is essential to protect both the antioxidants and any brightening result.

Guidance

Usage & Recommendations

How to Use

Smooth a few drops over the face after toner and before moisturizer, morning and evening. Because the serum already contains a five-form vitamin C complex, there is no need to layer a separate vitamin C product over it. In the morning, always follow with sunscreen — it protects both the antioxidants in the formula and the brightening result they are working toward. If pure vitamin C feels briefly sharp on reactive skin, begin with once-daily use and build up. The pore and elasticity benefits accumulate over six to eight weeks of consistent use, so steady application matters more than how much you apply at once; the 35 mL bottle rewards a measured few drops.

Value Assessment

At $31 for 35 mL, this serum is fairly but not generously priced. The bottle lasts roughly one and a half to two months with twice-daily use, putting it in mid-range territory for a treatment serum. The value case rests on the well-established actives — a five-form vitamin C complex, niacinamide and three peptides genuinely justify a good portion of the price. The PDRN and NMN are best regarded as on-trend extras rather than value drivers, so buyers should not pay the premium expecting them to deliver. There is no larger size. Compared with PDRN serums flooding the market at $30 to $70, Klairs's pricing is reasonable, and the brand's long, trustworthy track record in gentle formulation supports confidence. The value is solid if you buy it for the proven ingredients and treat the trend actives as a bonus.

Who Should Buy

People after a well-rounded brightening-and-pore serum who are curious about PDRN but sensible enough to treat it as a promising bonus rather than the headline — the vitamin C, niacinamide and peptides carry dependable weight. The lightweight, fragrance-free formula suits most skin types, including sensitive skin that wants actives without irritation.

Who Should Skip

Anyone buying primarily for PDRN should temper expectations, since topical PDRN evidence is still emerging. Very reactive skin should patch test given the pure ascorbic acid, and those who want a fungal-acne-safe routine should look elsewhere. Anyone expecting permanent pore shrinking will be disappointed, as no serum can deliver that.

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Details

Product Details

Texture

A lightweight, slightly gel-like serum that spreads easily and absorbs quickly to a smooth, non-tacky finish. It leaves skin feeling cushioned and plump rather than coated.

Scent

Fragrance-free, with a near-undetectable neutral note.

Packaging

35 mL bottle with a dropper, in Klairs's clean, minimalist design. The dropper allows controlled dosing; the opaque-leaning bottle gives some protection to the vitamin C and antioxidants.

Finish
lightweightfast-absorbingdewy
What to Expect on First Use

It goes on like a light, cushiony serum — absorbing fast and leaves skin looking plumper and a touch more radiant. Pure vitamin C can give reactive skin a brief, mild sharpness, but there is no lingering sting. The pore and elasticity benefits build quietly over weeks rather than appearing at once.

How Long It Lasts

About 1.5-2 months applied morning and night

Period After Opening

12 months

Opened yours? Track the toss-by date
Best Season

All Year

Background

The Story Behind This Product

PDRN became one of the most-hyped K-beauty ingredients of 2025, and Klairs's entry takes a notable angle: a vegan, plant-derived PDRN rather than the salmon-sourced original. The serum frames pore care as an elasticity problem — slack, less firm skin makes pores look larger — and stacks repair-and-firming actives to address that.

About Klairs Established Brand (5–20 years)

Dear, Klairs was founded in 2010 in Seoul under Wishcompany, with a philosophy of simple, gentle skincare for sensitive skin. The brand became globally recognized through its Supple Preparation line and has a long, well-reviewed track record in K-beauty.

Brand founded: 2010 · Product launched: 2025
Myth vs. Reality

Common Myths

Myth

PDRN in skincare is the same proven ingredient used in medical treatments.

Reality

PDRN has medical use in injectable form, where it reaches deeper skin layers. Topical PDRN, including the vegan Sodium DNA form here, is a different proposition — its ability to penetrate and act from a leave-on serum is still an emerging area of research. It is a promising trend ingredient, not a proven topical treatment.

Myth

A serum can shrink your pores permanently.

Reality

Pore size is largely genetic and influenced by oil production, sun damage and loss of skin firmness. This serum can make pores look smaller by clearing congestion, supporting elasticity and smoothing texture, but the change is cosmetic and maintained by consistent use, not a permanent shrinking.

FAQ

Frequently Asked Questions

What is PDRN in the Klairs Bouncy Pore Serum?

PDRN refers to polynucleotide-type actives associated with skin repair and elasticity. This serum uses a vegan, plant-derived form listed on the label as Sodium DNA, rather than the traditional salmon-sourced PDRN. Topical PDRN is a promising but still emerging trend ingredient, included here for the serum's firming, bouncy claim.

Does the Klairs PDRN serum actually minimize pores?

It can make pores look smaller over time. Niacinamide refines pores and controls oil, while the PDRN and peptides support skin elasticity, since slack skin makes pores appear larger. The improvement is cosmetic and gradual, building over six to eight weeks — it does not permanently shrink pores.

Can I use this serum with a separate vitamin C product?

There is no need to. The serum already contains a five-form vitamin C complex, so layering another vitamin C product on top is unnecessary and could increase the chance of irritation. Use this as your vitamin C step, and follow with moisturizer and, in the morning, sunscreen.

Is the Klairs PDRN serum good for sensitive skin?

It is fragrance-free and from a brand known for sensitive-skin care, with soothing centella in the formula. However, it does contain pure ascorbic acid, which can feel slightly sharp on reactive skin. Sensitive skin should introduce it gradually and patch test first.

Is the Klairs PDRN serum vegan?

Yes. Klairs uses a vegan, plant-derived PDRN (listed as Sodium DNA) rather than the salmon-derived PDRN traditional to the category, and the formula contains no other animal-derived ingredients. It is suitable for those following a vegan routine.

Reviews

What Reviewers Tend to Say

Recurring themes our editors read across retailer reviews of this product — summaries in our words, not quotations, and not a substitute for your own patch test.

Common Praise

Lightweight texture that absorbs quickly and layers well

Skin looks smoother and more radiant with regular use

Fragrance-free, in keeping with Klairs's sensitive-skin focus

Early users like the plumped, bouncy feel

Common Complaints

PDRN and NMN are trend ingredients with limited topical evidence

35 mL bottle is modest for twice-daily use

Pure vitamin C can feel slightly sharp on reactive skin

Pore results are gradual, not dramatic

Notable Endorsements
Sold at Amazon and major K-beauty retailersFeatured in 2025-2026 PDRN skincare roundups
Appears In
Serums That Suit DullnessSerums That Suit Large PoresBest Vitamin C Serums
Related Conditions
large poresdullnessagingrough texturedehydration
Related Ingredients
pdrnvitamin cniacinamidepeptidesastaxanthin