Cyclosporine (modified) (Gengraf, Neoral, Sandimmune) is a cyclic polypeptide immunosuppressant agent. Produced by the fungus species Beauveria nivea, cyclosporine and cyclosporine (modified) are in a class of medications called immunosuppressants. They work by decreasing the activity of the immune system – or suppressing the immune system, hence the name “immunosuppressant”. Cyclosporine (modified) is available by prescription to be taken orally in either capsule or solution (liquid) formulations. Cyclosporine and cyclosporine (modified) may cause side effects, some of which can be serious, and include but are not limited to bruising, pale skin, yellowing of the skin or eyes and seizures. Talk to your doctor if you experience unusual problems while taking either medication. Cyclosporine is an FDA pregnancy category C medication, which means that it is not known whether cyclosporine is harmful to an unborn human baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Further, if you are nursing tell your doctor before starting cyclosporine, as it’s not known if the drug can pass into breast milk.